Israeli PM Benjamin Netanyahu says his country will defend itself "against any attack" after it carried out what have been called its largest strikes against sites in Syria in decades.
"This is both our right and our duty and we will continue to do so as much as necessary," he said on Saturday.
Israel launched raids against Iranian targets after saying it had intercepted an Iranian drone.
Iran's presence in Syria has caused alarm in Israel.
Mr Netanyahu warned that Israel's policy to defend itself against "any attempt to harm our sovereignty" was "absolutely clear".
"Iran brazenly violated Israel's sovereignty," he said, adding: "They dispatched an Iranian drone from Syrian territory into Israel... Israel holds Iran and its Syrian hosts responsible."
Iran has denied Israel's allegations about the drone.
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